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Torsten Schwede
Computational Structural Biology Group
University of Basel
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At the Computational Structural Biology (CSB) Group we are focusing on the development of methods and algorithms to model, simulate and analyse three-dimensional protein structures and their molecular properties in order to apply these techniques to understanding biological processes at a molecular level. Our main emphasis is on homology modelling approaches – using evolutionary information to model protein tertiary and quaternary structures. Applications in biomedical research include the study of protein-ligand interactions from different perspectives, such as the identification of small antiviral molecules to support drug development, the structure-guided engineering of enzymes or the interpretation of disease causing mutations in proteins.

Our research topics: