Services

The BBCF collaborates with life science researchers and technological facilities to implement a high-quality data analysis and data management infrastructure while offering tailored analyses for complex data. The current focus of the group is on high-throughput sequencing for functional genomics with emphasis on applications to whole-genome sequencing for comparative genomics, analysis of bacterial communities, chromatin immunoprecipitation and sequencing (ChIP-seq), RNA sequencing (RNA-seq) and chromosome conformation analysis (4C-seq and HiC). Another strong interest of our group is the statistical analysis of time-series and multi-omics data integration.

Services

  • Analysis of large or complex data sets
  • Design and implementation of data management solutions for new high-throughput technologies (e.g. high-density arrays, high-throughput sequencing)
  • Statistical consulting and planning in complex experimental designs
  • Development of software and databases
  • Bioinformatics training for life science researchers

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Resources

The following resources have been developed in collaboration with various research groups and are maintained by the Core Facility:

HTSstation, a high-throughput sequencing data analysis portal
GenRep, a platform to manage reference genomic data
Bioscript, a genomic data processing system
BioRepo, a biological data repository for efficient management and storage of genomic data
SwissPalm, a database of protein S-palmitoylation
FlyGut, an atlas of the Drosophila adult midgut
BMC, a cytotoxicity data analysis server
PrimerViz, a gene and transcript-specific RT-PCR primer generator

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